Drug Allergy and Drug Response Testing (PGx) [GO233]

About This Service

Pharmacogenomics (PGx): Drug Allergy and Drug Response Testing
Why Is Pharmacogenomic Testing Important?

The same medication may not work equally well for everyone. Some individuals may also experience severe adverse drug reactions, such as blistering and peeling of the skin or anaphylactic shock, which can sometimes be life-threatening.

Pharmacogenomic (PGx) testing helps identify genetic variations that may affect how your body processes and responds to different medications.

Help prevent severe adverse drug reactions by identifying genetic risk factors associated with certain medications.
Support personalized medicine by helping physicians select appropriate medications and optimize dosages for greater safety and effectiveness.
Provide a lifelong medication reference to support informed treatment decisions throughout your life.
Potentially Life-Threatening Severe Adverse Drug Reactions
Stevens–Johnson Syndrome (SJS): A rare, serious reaction in which the immune system responds abnormally to a medication, causing inflammation and the death and detachment of skin cells and mucous membranes.
Toxic Epidermal Necrolysis (TEN): A severe, potentially life-threatening condition characterized by widespread skin detachment, resembling extensive burns.
DRESS / DHS (Drug Reaction with Eosinophilia and Systemic Symptoms / Drug Hypersensitivity Syndrome): A serious drug reaction that can affect multiple internal organs. Symptoms may persist or progress even after the causative medication has been discontinued and can be life-threatening.
Medication Groups Covered by This Test
Gout medications: Allopurinol
Anticonvulsants / Psychiatric medications: Carbamazepine or Oxcarbazepine
HIV antiviral medication: Abacavir
Dermatological / Leprosy medications: Dapsone or sulfonamide drugs
Tuberculosis medication: Isoniazid
Who Should Consider PGx Testing?
Individuals who are about to start medications associated with known genetic risks, such as gout medications, anticonvulsants, or tuberculosis medications.
Patients with chronic conditions (NCDs) who need to take multiple medications.
Individuals with a personal or family history of severe adverse drug reactions.
Health-conscious individuals, wellness enthusiasts, and biohackers who want deeper insights into their genetic health and take a proactive, preventive approach to medication safety.

Important Note: PGx testing identifies certain genetic risks that may influence medication response. It does not predict every drug allergy or adverse reaction, and a negative result does not guarantee that a medication is completely safe. Test results should be interpreted by a qualified healthcare professional alongside medical history and other clinical information.